Radiopharmaceuticals

Indications
• Hepatobiliary function studies
• Evaluation of bile flow, and diagnosis of extrahepatic biliary obstruction, malfunctioning gall-bladder, gall-bladder inflammation, biliary duct artresia, biliary cysts or similar pathologic alterations of the biliary duct.

Indications

The Tc-99m labelled compound can be used for static (planar or tomographic) renal imaging:

• Kidney scintigraphy, static imaging of kidney location
• Determination of functional kidney weight
• Determine the relative function (%) of the right and left kidneys

The Tc-99m labelled compound can be used for:
After labeling with sterile 99mTc-pertechnetate solution, it is indicated for:

• Determination of glomerular filtration (GFR)
• Visualization of the kidney by sequential scintigraphy
• Renal perfusion studies
• Urinary tract studies
• Renal artery stenosis
• Estimation of transplanted kidney function
• Vesico-urethral reflux
• Visualization of brain lesions (tumor, bleeding)
• Inhalation pulmonary scintigraphy (using a suitable nebulizer)

Indications

Regional cerebral blood flow (stroke, carotid artery occlusion, transient ischaemic attack, migraine, tumours of the brain, dementia differential diagnosis).

• HM-PAO kit can be applied for detection, localisation of cortical areas with decreased perfusion, and to estimate the extent of the damage.
• Detection of affected cortical areas over 1-2 cm is feasible by planar gamma camera, the smaller areas can be detected by SPECT.

Indications
Detection of inflammatory processes (based on white blood cell migration) in case of
• Bacterial infection
• Abscess
• Inflammatory lesions of the intestine, bones or joints

Indications
• Myocardial perfusion scintigraphy for the detection and localisation of coronary artery disease (angina pectoris and myocardial infarction)
• Assessment of global ventricular function. First-pass technique for determination of ejection fraction and/or ECG-triggered, gated SPECT for evaluation of left ventricular ejection fraction, volumes and regional wall motion.
• Scintimammography for the detection of suspected breast cancer when mammography is equivocal, inadequate or indeterminate.
• Localisation of hyperfunctioning parathyroid tissue in patients with recurrent or persistent disease in both primary and secondary hyperparathyroidism, and in patients with primary hyperparathyroidism scheduled to undergo initial surgery of the parathyroid glands.

Red Blood Cell Labelling

Indications
After radiolabelling with sodium (99mTc) pertechnetate solution, the solution obtained is indicated for
• Bone scintigraphy
• Cardiac scintigraphy, diagnosis of acute myocardial infarction After reconstitution with physiological sodium chloride solution in vivo or in vivo/in vitro red blood cell labelling for determination of blood volume and spleen scintigraphy.

Indications
The labelled MAA is suitable for

• Pulmonary perfusion scintigraphy
• Pulmonary embolism and myocardial infarct
• Chronic circulatory failure
• Local respiratory distress
• Emphysema
• Tumour
• Inflammation
• Visualisation of venous circulation
• Perfusion arterial scintigraphy of abdominal and retroperitoneal organs
• Detection of deep vein thrombosis in the lower extremities and pelvis
• Occlusion of the vena cava inferior

The kit contains sterile tubes and transfer pipettes for 3 complete leucocyte separations and labellings.

Indications

• Primary bone tumours imaging
• Bone metastases (e.g. prostate, breast, lung cancer)
• Osteomyelitis • metabolic bone disease
• Paget’s disease
• Fractures
• Avascular necrosis
• Loosened/inflamed arthricular prosthesis
• Arthricular inflammations (rheumatoid arthritis)

Indications
After reconstitution and labelling with sodium (99mTc) pertechnetate solution, the diagnostic agent technetium (99mTc) tiatide may be used intravenously for the evaluation of nephrological and urological disorders in particular for the study of morphology, perfusion, and function of the kidney and characterisation of urinary outflow.